Stanford molecule turns lymphoma's driver protein into a kill switch
Stanford Medicine researchers built a two-sided molecule, TCIP3, that grabs BCL6, the protein driving many B-cell lymphomas, and links it to enzymes that switch the cell's death genes on. In mice implanted with human lymphoma, twice-daily treatment made the tumors disappear within 11 days with no obvious toxicity. The Cell study is early, and much more testing is needed before it could reach patients.